@article{oai:repo.lib.tut.ac.jp:00001178,
 author = {ヤスダ, ヨシフミ and タケウチ, ハヤト and サイト, ヨシヒロ and 安田, 好文 and 竹内, 隼人 and 齊戸, 美弘 and Yasuda, Yoshifumi and Takeuchi, Hayato and Saito, Yoshihiro},
 journal = {雲雀野, The Lark Hill},
 month = {Mar},
 note = {P(論文), Carbon monoxide （CO） concentration in the blood is measured by a headspace
method with a gas-chromatography （HS-GC） and/or a CO-oximeter. However, the
deficiencies of using HS-GC, especially on blood CO analysis, are not well
documented. In the present study the effect of these deficiencies and the agreement
of the results between the HS-GC and CO-oximeter methods were examined. Results
indicated, in the application of HS-GC for blood CO analysis, that the TRIlyzer, a
simplified gas chromatograph used in this study, showed a high linearity and
reproducibility. The use of a surfactant such as Triton enhanced destruction of the
plasma membrane of the erythrocytes and thereby increased blood CO values.
Furthermore, an alkaline buffer solution provided higher blood CO values compared
with those of an acid buffer solution. Correlation analysis between the results obtained
by HS-GC and CO-oximeter on four subjects, including smokers and non-smokers,
also revealed a significant relationship （r= 0.954） between them. However, the
correlation coefficient （r） between CO concentrations during and after exercise
measured by HS-GC and CO-oximeter on each subject showed a negative correlation
for three of the four subjects. It is suggested that, in the application of HS-GC, a
surfactant and an alkaline buffer solution should be used in the blood CO analysis, but
discrepancies still remain between the values obtained by HS-GC and CO-oximeter.
Therefore, further studies will be required to obtain clear agreement between the
methods.},
 pages = {47--55},
 title = {ヘッドスペース法を用いた血中一酸化炭素濃度測定の有効性},
 volume = {35},
 year = {2013}
}